In American politics, medical innovation is often considered the domain of the private sector. Yet some of the most significant scientific and health breakthroughs of the past century have emerged from government research institutes. The U.S. National Cancer Institute (NCI) is tasked with both understanding and eradicating cancer—and its researchers have developed a surprising expertise in virus research and vaccine development. An Ungovernable Foe examines seventy years of federally funded scientific breakthroughs in the laboratories of the NCI to shed new light on how bureaucratic organizations nurture innovation. Natalie B. Aviles analyzes research and policy efforts around the search for a viral cause of leukemia in the 1960s, the discovery of HIV and the development of AIDS drugs in the 1980s, and the invention of the HPV vaccine in the 1990s. She argues that the NCI transformed generations of researchers into innovative public servants who have learned to balance their scientific and bureaucratic missions. These “scientist-bureaucrats” are simultaneously committed to conducting cutting-edge research and stewarding the nation’s investment in cancer research, and as a result they have developed an unparalleled expertise. Aviles demonstrates how the interplay of science, politics, and administration shaped the NCI into a mission-oriented agency that enabled significant breakthroughs in cancer research—and in the process, she shows how organizational cultures indelibly stamp scientific work.

What is the value of comparison for research in historical sociology? Today, social scientists regularly express doubt about the positivist premises that have long justified comparison’s use: that cases can be unproblematically compared as though they are independent of one another, that comparison can reliably yield valid causal inference, and that comparative methods can grapple with questions of meaning, sequence, and process that are central to historical explanation. Yet they remain reluctant to abandon comparison altogether, not least because comparisons are still manifestly useful in the research process. After Positivism presents a bold new set of warrants and methodologies for comparison that takes these criticisms fully into account. The contributors to this book marshal a wide array of postpositivist approaches to knowledge to reconstruct the analytic potential of comparison for a new generation of social scientists. In addition to providing fresh answers to classic questions about case selection and causal inference, authors ponder the role comparison plays in a world where social phenomena are demonstrably time-, space-, and concept-dependent; where causation is typically conjunctural; where social structures and groups emerge and die; and where important objects of inquiry can be understood only in terms of relationships, emergent properties, or contingent and irregular effects. Engaging and timely, this book will be of interest to all those who seek to improve our explanations of historical change in social-scientific research.

Reproduction of the original: What’s-His-Name by George Barr McCutcheon

South Africa is awash with policy failures, and policy confusion. We argue firstly, that our current discord over policy details has its origin in the (celebrated) negotiated transition. We hold that the vote count of an 85% majority in the Constituent Assembly in 1996 obscured the reality that the Constitution meant different things to different negotiators. The result was that South Africa, from the very start of the democratic era, lacked a national consensus on how to go about consolidating democracy. We keep on failing to build a proper roof over our democracy because the constitutional foundations are weak.ÿ

The Unruly Tongue in Early Modern England is a scholarly edition of three early modern treatises on the unruly tongue: Jean de Marconville, A Treatise of the Good and Evell Tounge (ca.1592), William Perkins, A Direction for the Government of the Tongue according to Gods worde (1595), and George Webbe, The Araignement of an unruly Tongue (1619). “The tongue can no man tame” says the Bible (James 3:8), and yet these texts try to tame the tongues of men and tell them how they should rule this little but essential organ and avoid swearing, blaspheming, cursing, lying, flattering, railing, slandering, quarrelling, babbling, jesting, or mocking. This volume excavates the biblical and classical sources in which these early modern texts are embedded and gives a panorama of the sins of the tongue that the Elizabethan society both cultivates and strives to contain. Vienne-Guerrin provides the reader with early modern images of what Erasmus described as a “slippery” and “ambivalent” organ that is both sweet and sour, a source of life and death.