Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available

Students often find it difficult to grasp fundamental ecologicaland evolutionary concepts because of their inherently mathematicalnature. Likewise, the application of ecological and evolutionarytheory often requires a high degree of mathematical competence. This book is a first step to addressing these difficulties,providing a broad introduction to the key methods and underlyingconcepts of mathematical models in ecology and evolution. The bookis intended to serve the needs of undergraduate and postgraduateecology and evolution students who need to access the mathematicaland statistical modelling literature essential to theirsubjects. The book assumes minimal mathematics and statistics knowledgewhilst covering a wide variety of methods, many of which are at thefore-front of ecological and evolutionary research. The book alsohighlights the applications of modelling to practical problems suchas sustainable harvesting and biological control. Key features: Written clearly and succinctly, requiring minimal in-depthknowledge of mathematics Introduces students to the use of computer models in bothfields of ecology and evolutionary biology Market - senior undergraduate students and beginningpostgraduates in ecology and evolutionary biology

Students often find it difficult to grasp fundamental ecological and evolutionary concepts because of their inherently mathematical nature. Likewise, the application of ecological and evolutionary theory often requires a high degree of mathematical competence. This book is a first step to addressing these difficulties, providing a broad introduction to the key methods and underlying concepts of mathematical models in ecology and evolution. The book is intended to serve the needs of undergraduate and postgraduate ecology and evolution students who need to access the mathematical and statistical modelling literature essential to their subjects. The book assumes minimal mathematics and statistics knowledge whilst covering a wide variety of methods, many of which are at the fore-front of ecological and evolutionary research. The book also highlights the applications of modelling to practical problems such as sustainable harvesting and biological control. Key features: Written clearly and succinctly, requiring minimal in-depth knowledge of mathematics Introduces students to the use of computer models in both fields of ecology and evolutionary biology Market - senior undergraduate students and beginning postgraduates in ecology and evolutionary biology

Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available

An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Mathematical ecology is the application of mathematics to describe and understand ecosystems. There are two main approaches. One is to describe natural communities and induce statistical patterns or relationships which should generally occur. However, this book is devoted entirely to introducing the student to the second approach: to study deterministic mathematical models and, on the basis of mathematical results on the models, to look for the same patterns or relationships in nature. This book is a compromise between three competing desiderata. It seeks to: maximize the generality of the models; constrain the models to "behave" realistically, that is, to exhibit stability and other features; and minimize the difficulty of presentations of the models. The ultimate goal of the book is to introduce the reader to the general mathematical tools used in building realistic ecosystem models. Just such a model is presented in Chapter Nine. The book should also serve as a stepping-stone both to advanced mathematical works like Stability of Biological Communities by Yu. M. Svirezhev and D. O. Logofet (Mir, Moscow, 1983) and to advanced modeling texts like Freshwater Ecosystems by M. Straskraba and A. H. Gnauch (Elsevier, Amsterdam, 1985).

This volume discusses the rich and interesting properties of dynamical systems that appear in ecology and environmental sciences. It provides a fascinating survey of the theory of dynamical systems in ecology and environmental science. Each chapter introduces students and scholars to the state-of-the-art in an exciting area, presents new results, and inspires future contributions to mathematical modeling in ecology and environmental sciences.