Amphioxus Immunity
Title | Amphioxus Immunity PDF eBook |
Author | An-Long Xu |
Publisher | Elsevier |
Total Pages | 306 |
Release | 2015-12-31 |
Genre | Medical |
ISBN | 0128096470 |
Amphioxus Immunity: Tracing the Origin of Human Immunity covers a remarkable range of information about Amphioxus and its evolutionary context. This compilation of what is currently known about Amphioxus, with a sharp focus on its immune system, includes 13 topics, such as: Amphioxus as a model for understanding the evolution of vertebrates basic knowledge of immunology immune organs and cells of amphioxus a genomic and transcriptomic view of the Amphioxus immunity pattern recognition system in Amphioxus transcription factors in Amphioxus the complement system of Amphioxus the oxidative burst system in Amphioxus immune effectors in Amphioxus lipid signaling of immune response in Amphioxus apoptosis in amphioxus; primitive adaptive immune system of Amphioxus and future research directions This valuable reference book is loaded with information that will be useful for anyone who wishes to learn more about the origin of vertebrates and adaptive immunity. Provides new evidence on the origin of the adaptive immune system, the evolution of innate immunity, and evolution-stage specific immune defense mechanisms Not only presents the cells and molecules involved in the adaptive immune response in Amphioxus, but also characterizes the origination and evolution of the gene families and pathways involved in innate immunity Includes much pioneering work, from the molecular, genomic, and cellular to the individual level
Amphioxus Immunity
Title | Amphioxus Immunity PDF eBook |
Author | Anlong Xu |
Publisher | |
Total Pages | 303 |
Release | 2011 |
Genre | Amphioxus |
ISBN | 9787030323163 |
Advances in Comparative Immunology
Title | Advances in Comparative Immunology PDF eBook |
Author | Edwin L. Cooper |
Publisher | Springer |
Total Pages | 1048 |
Release | 2018-08-07 |
Genre | Medical |
ISBN | 3319767682 |
Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine.
Targeting the Innate Immune System to Develop Prophylactic Strategies
Title | Targeting the Innate Immune System to Develop Prophylactic Strategies PDF eBook |
Author | Jie Ji |
Publisher | |
Total Pages | 231 |
Release | 2017 |
Genre | |
ISBN |
Evolution of Innate Immunity in Eukarya: Advances and Implications
Title | Evolution of Innate Immunity in Eukarya: Advances and Implications PDF eBook |
Author | Jean L. Scholz |
Publisher | Frontiers Media SA |
Total Pages | 173 |
Release | 2022-05-06 |
Genre | Medical |
ISBN | 2889761339 |
Issues in Immunology Research: 2011 Edition
Title | Issues in Immunology Research: 2011 Edition PDF eBook |
Author | |
Publisher | ScholarlyEditions |
Total Pages | 1988 |
Release | 2012-01-09 |
Genre | Medical |
ISBN | 146496405X |
Issues in Immunology Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immunology Research. The editors have built Issues in Immunology Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunology Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
The M2 Macrophage
Title | The M2 Macrophage PDF eBook |
Author | Tamás Röszer |
Publisher | Springer Nature |
Total Pages | 224 |
Release | 2020-08-03 |
Genre | Medical |
ISBN | 3030504808 |
Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of immunity, tissue development and turnover, metabolism, and endocrine signaling. Dysfunction in M2 macrophages can ruin the healthy interplay between the immune system and metabolic processes, and lead to diseases such as insulin resistance, metabolic syndrome, and type 1 and 2 diabetes mellitus. Furthermore, M2 macrophages are essential for healthy tissue development and immunological self-tolerance. Worryingly, these functions of M2 macrophages can also be disrupted, resulting in tumor growth and autoimmunity. This book comprehensively discusses the biology of M2 macrophages, summarizes the current state of knowledge, and highlights key questions that remain unanswered.