The plant factory is a facility that aids the steady production of high-quality vegetables all year round by artificially controlling the cultivation environment (e.g., light, temperature, humidity, carbon dioxide concentration, and culture solution), allowing growers to plan production. By controlling theinternal environment,plant factories can produce vegetables about two to four times faster than by typical outdoor cultivation. In addition, as multiple cultivation shelves (a multi-shelf system) are used, the mass production of vegetables in a small space is facilitated. This research topic presents some new trends on intelligent measuring systems; environment controlled and optimization; flavonoids; phenylpropanoids, transcriptomes, and bacteria.

A comprehensive, practical text which covers a diverse range of hydroponic and protected cropping techniques, systems, greenhouse types and environments. It also details the use of indoor plant factories, vertical systems, organic hydroponics and aquaponics. Worldwide hydroponic cropping operations can vary from large, corporate producers running many hectares of greenhouse systems particularly for crops such as tomato, cucumber, capsicum and lettuce, to smaller-scale growers growing fresh produce for local markets.

This book describes the concept, characteristics, methodology, design, management, business, recent advances and future technologies of plant factories with artificial lighting (PFAL) and indoor vertical farms. The third wave of PFAL business started in around 2010 in Japan and Taiwan, and in USA and Europe it began in about 2013 after the rapid advances in LED technology. The book discusses the basic and advanced developments in recent PFALs and future smart PFALs that emerged in 2016. There is an emerging interest around the globe in smart PFAL R&D and business, which are expected to play an important role in urban agriculture in the coming decades. It is also expected that they will contribute to solving the trilemma of food, environment and natural resources with increasing urban populations and decreasing agricultural populations and arable land area. Current obstacles to successful PFAL R&D and business are: 1) no well-accepted concepts and methodology for PFAL design and management, 2) lack of understanding of the environmental effects on plant growth and development and hydroponics among engineers; 3) lack of understanding of the technical and engineering aspects of PFAL among horticulturists; 4) lack of knowledge of the technical challenges and opportunities in future PFAL businesses among business professionals, policy makers, and investors and 5) lack of a suitable textbook on the recent advances in PFAL technologies and business for graduate students and young researchers. This book covers all the aspects of successful smart PFAL R & D and business.

This book offers a timely yet comprehensive snapshot of innovative research and developments in the area of manufacturing. It covers a wide range of manufacturing processes, such as cutting, coatings, and grinding, highlighting the advantages provided by the use of new materials and composites, as well as new methods and technologies. It discusses topics in energy generation and pollution prevention. It shows how computational methods and mathematical models have been applied to solve a number of issues in both theoretical and applied research. Based on selected papers presented at the Grabchenko’s International Conference on Advanced Manufacturing Processes (InterPartner-2019), held in Odessa, Ukraine on September 10-13, 2019, this book offers a timely overview and extensive information on trends and technologies in the area of manufacturing, mechanical and materials engineering. It is also intended to facilitate communication and collaboration between different groups working on similar topics, and to offer a bridge between academic and industrial researchers.

Since 1972, which marks the invention of recombinant engineering, more than 500 therapeutic proteins have been approved for clinical use. Today, biological drugs constitute almost 70% of all new drugs and have a biological origin. The first edition of this book dealt with biosimilars, and this edition (i.e., the second edition) focuses on new drugs, yet limits to therapeutic proteins. Newer technologies for drug development represent the updated topics in the book and include repur-posing, AI- driven identification of newer designs, novel expression systems, manufacturing using these systems, rapidly changing regulatory pathways, and legal hurdles. This edition discusses how to identify, develop, manufacture, and take multibillion dollar products to market within the shortest possible time. Features: Complete and thorough coverage of the regulatory and technological challenges of developing generic therapeutic proteins Comprehensive, discovery to market, newer technologies, regulatory planning and IP hurdles are included that are not found elsewhere Expanded volume that must be in the hands of every company interested in biological drugs, including the mRNA-based biopharmaceutical companies fast appearing on the market Discusses how to identify, develop, manufacture, and take multibillion dollar products to market in the shortest possible time Renowned author and entrepreneur in the field of drug discovery and production

Recent Developments in Applied Microbiology and Biochemistry, Vol. 2, provides a comprehensive treatment and understanding on application oriented microbial concepts, giving readers insights into recent developments in microbial biotechnology and medical, agricultural and environmental microbiology. Discusses microbial proteome analyses and their importance in medical microbiology Explores emerging trends in the prevention of current global health problems, such as cancer, obesity and immunity Shows recent approaches in the production of novel enzymes from environmental samples by enrichment culture and metagenomics approaches Guides readers through the status and recent developments in analytical methods for the detection of foodborne microorganisms