ASR Index is a complete and detailed index of everything that has appeared in the Antique Studebaker Review magazine since its inception in 1971. Of greatest importance are the advice items that are indexed by subject (engines, brakes, steering, etc.). Historical items are also indexed by subject as well as by the vehicle (model and year) they relate to. If you own, for instance, a 1939 Champion, ASR Index will give you instant access to everything that has been published about your car and much more. Indexed by model, year, AND subject matter, ASR Index is detailed and comprehensive, making it easy to find the information you need. Each listing, of course, refers you to the specific issue of Antique Studebaker Review and cites the page on which the item begins. ASR Index includes issues of Antique Studebaker Review from 1971 through 2019 by subject, model, and year. It contains more than 4,300 references on 55 pages.

In recent years attention has been drawn on changes in multiple sclerosis (MS) prevalence according to sex and age. We are now aware that MS is not a disease with onset exclusively in the young adult, but that pediatric cases are not infrequent, as well as onset in older adults. The need to assess the role of aging, sexual hormones, diet, and infections, has boosted research in many areas, from immunology to imaging techniques to psychology. An increasing awareness of the impact of MS on personal and sexual relationships, with the need to assess patient related outcomes also in clinical trials, has driven research not only in psychology, but in many other areas. The need to integrate information from all these different research areas is deeply felt.

A study of how states can lawfully react to malicious cyber conduct, taking into account the problem of timely attribution.

Given the success of Volume I of this Research Topic, we are pleased to announce the launch of Volume II: “The Alzheimer's Disease Challenge”. The repeated failure of clinical trials on the amyloid-based medications and the pessimistic calculations of Alzheimer's disease cost burden for the next few decades present a severe challenge to humankind with severe social implications. In recent years, several alternative diagnostic and treatment procedures have been presented to treat and manage Alzheimer’s disease as it has been nearly impossible to suggest a holistic solution. Several revelations in human biology have highlighted the multiparametric character of the disease. Besides the amyloid aggregation and neurofibrillary tangles that result in Aβ toxicity and tau phosphorylation, processes such as Gene Mutations, Proteins Misfolding, Brain Biochemical and Histopathological Changes, Behavioral Changes, Nutrition and Metabolism Alterations, and Autonomic Dysfunctions due to Central Nervous System dysregulations are common signs and probably early diagnostic biomarkers in most of the Alzheimer's classification categories.